Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave

Ana María Haro-Pérez; Vega Estíbaliz Benito-López; Mar Jiménez-Rodríguez; Saray Martín-Monteagudo

doi:doi:10.11648/j.ijidt.20210604.11

| Peer-Reviewed

Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave

Ana María Haro-Pérez, Vega Estíbaliz Benito-López, Mar Jiménez-Rodríguez, Saray Martín-Monteagudo

Published in International Journal of Infectious Diseases and Therapy (Volume 6, Issue 4)

Received: 26 June 2021 Accepted: 7 July 2021 Published: 5 October 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Objective: Establish the characteristics and number of patients with a diagnosis of SARS-COV-2 who end up requiring hospital admission, and which of them require assistance in Intensive Care Units (ICU), and determine the time that passes from diagnosis to hospitalization. Compare our own health data between the different waves to see how the pandemic is evolving to manage healthcare resources. Methods: Retrospective observational epidemiological study of 517 COVID-19 patients, microbiologically confirmed, in a tertiary hospital, between June 1 and November 30, 2020. Results: The diagnosis of SARS-COV-2 infection was made by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in 78% of the cases, and by Antigen (Ag) test in the rest. In patients who presented symptoms, an average of 3 days elapsed until diagnosis. In asymptomatic patients, the time from the positive test to the onset of symptoms was 8.4 days on average in the cases of screening and 1 day in the case of contact studies. The mean time from the onset of symptoms to hospital admission was 9 days, 15.3 days in the cases detected by screening and 7.8 days in contact studies. The average hospital stay was 10 days and there was an overall mortality of 13%. 10% of the positive patients needed intensive care, where the average stay was 21 days, the median age was 61 years, and the mortality was 21%. Conclusions: A high percentage of patients diagnosed with SARS-COV-2 infection in Primary Care will require hospitalization (70% according to our study). This information is essential to anticipate the need for hospital resources and the time frame in which they will be needed.

Published in	International Journal of Infectious Diseases and Therapy (Volume 6, Issue 4)
DOI	10.11648/j.ijidt.20210604.11
Page(s)	119-125
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Hospitalization, Pandemics

References

[1]	Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia. New England Journal of Medicine. 2020; 382 (13): 1199-207.
[2]	Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020; 395 (10223): 507-13.
[3]	Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome. 23 January 2020 [cited 7 of February 2020]; Available in: http://www.ncbi.nlm.nih.gov/nuccore/MN908947.3
[4]	World Health Organization. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) [Internet]. 2020. Available in: https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-COVID-19-final-report.pdf.
[5]	Spanish Secretary of State for Health. Alert Coordination Center and Health Emergencies. Situation report12/31/2020. Available in: https://webcache.googleusercontent.com/search?q=cache:T4DiLsJ7CbgJ:https://www.mscbs.gob.es/profesionales/saludPublica/ccayes/alertasActual/nCov/documentos/Actualizacion_282_COVID-19.pdf+&cd=5&hl=es&ct=clnk&gl=es&client=firefox-b-e.
[6]	Novel Coronavirus (2019-nCoV) situation reports 2021. [Internet]. Available in: https://www.mscbs.gob.es/profesionales/saludPublica/ccayes/alertasActual/nCov/documentos/ITCoronavirus.pdf.
[7]	Ochoa C, Garmendia JR, Pérez MJ et al. Impacto de la COVID-19 en la mortalidad de la comunidad autónoma de Castilla y León. Gaceta Sanitaria. 2020. https://doi. org/10.1016/j.gaceta.2020.04.009.
[8]	National Epidemiological Surveillance Network. Situation of COVID-19 in Spain. Situation report 08/27/2020. [Internet]. 2020. Available in: https://www.isciii.es/QueHacemos/Servicios/VigilanciaSaludPublicaRENAVE/EnfermedadesTransmisibles/Documents/INFORMES/Informes%20COVID-19/Informe%20COVID-19.%20N%c2%ba%2041_27agosto2020_ISCIII.pdf.
[9]	Revealed: the long-term severe effects of COVID-19 that could go on for months [Internet]. Available in: https://www.telegraph.co.uk/global-health/science-and-disease/revealed-long-term-severe-effects-COVID-19-can-go-months/.
[10]	Ministerio de Sanidad. Estrategia de detección precoz, vigilancia y control de COVID-19 [Internet]. 2020. Available in: https://www.mscbs.gob.es/profesionales/saludPublica/ccayes/alertasActual/nCov/documentos/COVID-19_Estrategia_vigilancia_y_control_e_indicadores.pdf.
[11]	Martos Pérez F, Luque del Pino J, Jiménez García N, Mora Ruiz E, Asencio Méndez C, García Jiménez JM, et al. Comorbilidad y factores pronósticos al ingreso en una cohorte COVID-19 de un hospital general. Rev Clin Esp. 2020, Jun 26. doi: 10.1016/j.rce.2020.05.017.
[12]	Ferrando C, Mellado-Artigas R, Gea A, Arruti E, Aldecoa C, Bordell A, et al. Características, evolución clínica y factores asociados a la mortalidad en UCI de los pacientes críticos infectados por SARS-COV-2 en España: estudio prospectivo, de cohorte y multicéntrico. Rev Esp Anestesiol Reanim. 2020; 67 (8): 425-37. doi: 10.1016/j.redar.2020.07.003.
[13]	Louie JK, Stoltey JE, Scott HM, Trammell S, Ememu E, Samuel MC, et al. Comparison of symptomatic and asymptomatic infections due to severe acute respiratory coronavirus virus 2 (SARS-COV-2) in San Francisco long-term care facilities. Infection Control & Hospital Epidemiology. undefined/ed; 1-3.
[14]	Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020; 395 (10229): 1054-62.
[15]	McAloon C, Collins Á, Hunt K, Barber A, Byrne AW, Butler F, et al. Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research. BMJ Open. 2020; 10 (8): e039652.
[16]	Bai Y, Yao L, Wei T, Tian F, Jin D-Y, Chen L, et al. Presumed Asymptomatic Carrier Transmission of COVID-19. JAMA. 2020; 323 (14): 1406.
[17]	Tindale LC, Coombe M, Stockdale JE, Garlock ES, Lau WYV, Saraswat M, et al. Transmission interval estimates suggest pre-symptomatic spread of COVID-19. medRxiv. 6 March 2020; 2020. 03. 03. 20029983.

Cite This Article

Plain Text BibTeX RIS

APA Style

Ana María Haro-Pérez, Vega Estíbaliz Benito-López, Mar Jiménez-Rodríguez, Saray Martín-Monteagudo. (2021). Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. International Journal of Infectious Diseases and Therapy, 6(4), 119-125. https://doi.org/10.11648/j.ijidt.20210604.11

Copy | Download

ACS Style

Ana María Haro-Pérez; Vega Estíbaliz Benito-López; Mar Jiménez-Rodríguez; Saray Martín-Monteagudo. Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. Int. J. Infect. Dis. Ther. 2021, 6(4), 119-125. doi: 10.11648/j.ijidt.20210604.11

Copy | Download

AMA Style

Ana María Haro-Pérez, Vega Estíbaliz Benito-López, Mar Jiménez-Rodríguez, Saray Martín-Monteagudo. Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. Int J Infect Dis Ther. 2021;6(4):119-125. doi: 10.11648/j.ijidt.20210604.11

Copy | Download

@article{10.11648/j.ijidt.20210604.11,
  author = {Ana María Haro-Pérez and Vega Estíbaliz Benito-López and Mar Jiménez-Rodríguez and Saray Martín-Monteagudo},
  title = {Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {6},
  number = {4},
  pages = {119-125},
  doi = {10.11648/j.ijidt.20210604.11},
  url = {https://doi.org/10.11648/j.ijidt.20210604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20210604.11},
  abstract = {Objective: Establish the characteristics and number of patients with a diagnosis of SARS-COV-2 who end up requiring hospital admission, and which of them require assistance in Intensive Care Units (ICU), and determine the time that passes from diagnosis to hospitalization. Compare our own health data between the different waves to see how the pandemic is evolving to manage healthcare resources. Methods: Retrospective observational epidemiological study of 517 COVID-19 patients, microbiologically confirmed, in a tertiary hospital, between June 1 and November 30, 2020. Results: The diagnosis of SARS-COV-2 infection was made by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in 78% of the cases, and by Antigen (Ag) test in the rest. In patients who presented symptoms, an average of 3 days elapsed until diagnosis. In asymptomatic patients, the time from the positive test to the onset of symptoms was 8.4 days on average in the cases of screening and 1 day in the case of contact studies. The mean time from the onset of symptoms to hospital admission was 9 days, 15.3 days in the cases detected by screening and 7.8 days in contact studies. The average hospital stay was 10 days and there was an overall mortality of 13%. 10% of the positive patients needed intensive care, where the average stay was 21 days, the median age was 61 years, and the mortality was 21%. Conclusions: A high percentage of patients diagnosed with SARS-COV-2 infection in Primary Care will require hospitalization (70% according to our study). This information is essential to anticipate the need for hospital resources and the time frame in which they will be needed.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave
AU  - Ana María Haro-Pérez
AU  - Vega Estíbaliz Benito-López
AU  - Mar Jiménez-Rodríguez
AU  - Saray Martín-Monteagudo
Y1  - 2021/10/05
PY  - 2021
N1  - https://doi.org/10.11648/j.ijidt.20210604.11
DO  - 10.11648/j.ijidt.20210604.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 119
EP  - 125
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20210604.11
AB  - Objective: Establish the characteristics and number of patients with a diagnosis of SARS-COV-2 who end up requiring hospital admission, and which of them require assistance in Intensive Care Units (ICU), and determine the time that passes from diagnosis to hospitalization. Compare our own health data between the different waves to see how the pandemic is evolving to manage healthcare resources. Methods: Retrospective observational epidemiological study of 517 COVID-19 patients, microbiologically confirmed, in a tertiary hospital, between June 1 and November 30, 2020. Results: The diagnosis of SARS-COV-2 infection was made by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in 78% of the cases, and by Antigen (Ag) test in the rest. In patients who presented symptoms, an average of 3 days elapsed until diagnosis. In asymptomatic patients, the time from the positive test to the onset of symptoms was 8.4 days on average in the cases of screening and 1 day in the case of contact studies. The mean time from the onset of symptoms to hospital admission was 9 days, 15.3 days in the cases detected by screening and 7.8 days in contact studies. The average hospital stay was 10 days and there was an overall mortality of 13%. 10% of the positive patients needed intensive care, where the average stay was 21 days, the median age was 61 years, and the mortality was 21%. Conclusions: A high percentage of patients diagnosed with SARS-COV-2 infection in Primary Care will require hospitalization (70% according to our study). This information is essential to anticipate the need for hospital resources and the time frame in which they will be needed.
VL  - 6
IS  - 4
ER  -

Copy | Download

Author Information

Ana María Haro-Pérez

Area of Preventive Medicine and Public Health, University Hospital of Salamanca, Salamanca, Spain
Vega Estíbaliz Benito-López

Area of Preventive Medicine and Public Health, University Hospital of Salamanca, Salamanca, Spain
Mar Jiménez-Rodríguez

Area of Preventive Medicine and Public Health, University Hospital of Salamanca, Salamanca, Spain
Saray Martín-Monteagudo

Area of Preventive Medicine and Public Health, University Hospital of Salamanca, Salamanca, Spain

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Ana María Haro-Pérez, Vega Estíbaliz Benito-López, Mar Jiménez-Rodríguez, Saray Martín-Monteagudo. (2021). Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. International Journal of Infectious Diseases and Therapy, 6(4), 119-125. https://doi.org/10.11648/j.ijidt.20210604.11

Copy | Download

ACS Style

Ana María Haro-Pérez; Vega Estíbaliz Benito-López; Mar Jiménez-Rodríguez; Saray Martín-Monteagudo. Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. Int. J. Infect. Dis. Ther. 2021, 6(4), 119-125. doi: 10.11648/j.ijidt.20210604.11

Copy | Download

AMA Style

Ana María Haro-Pérez, Vega Estíbaliz Benito-López, Mar Jiménez-Rodríguez, Saray Martín-Monteagudo. Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave. Int J Infect Dis Ther. 2021;6(4):119-125. doi: 10.11648/j.ijidt.20210604.11

Copy | Download

@article{10.11648/j.ijidt.20210604.11,
  author = {Ana María Haro-Pérez and Vega Estíbaliz Benito-López and Mar Jiménez-Rodríguez and Saray Martín-Monteagudo},
  title = {Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {6},
  number = {4},
  pages = {119-125},
  doi = {10.11648/j.ijidt.20210604.11},
  url = {https://doi.org/10.11648/j.ijidt.20210604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20210604.11},
  abstract = {Objective: Establish the characteristics and number of patients with a diagnosis of SARS-COV-2 who end up requiring hospital admission, and which of them require assistance in Intensive Care Units (ICU), and determine the time that passes from diagnosis to hospitalization. Compare our own health data between the different waves to see how the pandemic is evolving to manage healthcare resources. Methods: Retrospective observational epidemiological study of 517 COVID-19 patients, microbiologically confirmed, in a tertiary hospital, between June 1 and November 30, 2020. Results: The diagnosis of SARS-COV-2 infection was made by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in 78% of the cases, and by Antigen (Ag) test in the rest. In patients who presented symptoms, an average of 3 days elapsed until diagnosis. In asymptomatic patients, the time from the positive test to the onset of symptoms was 8.4 days on average in the cases of screening and 1 day in the case of contact studies. The mean time from the onset of symptoms to hospital admission was 9 days, 15.3 days in the cases detected by screening and 7.8 days in contact studies. The average hospital stay was 10 days and there was an overall mortality of 13%. 10% of the positive patients needed intensive care, where the average stay was 21 days, the median age was 61 years, and the mortality was 21%. Conclusions: A high percentage of patients diagnosed with SARS-COV-2 infection in Primary Care will require hospitalization (70% according to our study). This information is essential to anticipate the need for hospital resources and the time frame in which they will be needed.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Progression of SARS-COV-2 Infection in Patients Requiring Hospital Admission During the Second COVID-19 Pandemic Wave
AU  - Ana María Haro-Pérez
AU  - Vega Estíbaliz Benito-López
AU  - Mar Jiménez-Rodríguez
AU  - Saray Martín-Monteagudo
Y1  - 2021/10/05
PY  - 2021
N1  - https://doi.org/10.11648/j.ijidt.20210604.11
DO  - 10.11648/j.ijidt.20210604.11
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 119
EP  - 125
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20210604.11
AB  - Objective: Establish the characteristics and number of patients with a diagnosis of SARS-COV-2 who end up requiring hospital admission, and which of them require assistance in Intensive Care Units (ICU), and determine the time that passes from diagnosis to hospitalization. Compare our own health data between the different waves to see how the pandemic is evolving to manage healthcare resources. Methods: Retrospective observational epidemiological study of 517 COVID-19 patients, microbiologically confirmed, in a tertiary hospital, between June 1 and November 30, 2020. Results: The diagnosis of SARS-COV-2 infection was made by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in 78% of the cases, and by Antigen (Ag) test in the rest. In patients who presented symptoms, an average of 3 days elapsed until diagnosis. In asymptomatic patients, the time from the positive test to the onset of symptoms was 8.4 days on average in the cases of screening and 1 day in the case of contact studies. The mean time from the onset of symptoms to hospital admission was 9 days, 15.3 days in the cases detected by screening and 7.8 days in contact studies. The average hospital stay was 10 days and there was an overall mortality of 13%. 10% of the positive patients needed intensive care, where the average stay was 21 days, the median age was 61 years, and the mortality was 21%. Conclusions: A high percentage of patients diagnosed with SARS-COV-2 infection in Primary Care will require hospitalization (70% according to our study). This information is essential to anticipate the need for hospital resources and the time frame in which they will be needed.
VL  - 6
IS  - 4
ER  -

Copy | Download