Volume 5, Issue 3, September 2020, Page: 56-63
The Rates of the Unnecessary Antimicrobial Use (UAU) and the Effect of the Infectious Disease Consultations: A Cross-Sectional Study
Jamal Wadi Al Ramahi, School of Medicine, The University of Jordan, Amman, Jordan; Department of Medicine, The Specialty Hospital, Amman, Jordan; Department of Infection Control and Prevention, Al Khalidi Hospital and Medical Center, Amman, Jordan
Oday Abu Ajamieh, Department of Medicine, The Specialty Hospital, Amman, Jordan
Nadine Marrar, Department of Pharmacy, The Specialty Hospital, Amman, Jordan
Lana Alalamat, Department of Medicine, Jordan Hospital Medical Center, Amman, Jordan
Nour Hasan, Department of Pharmacy, Al Khalidi Hospital and Medical Center, Amman, Jordan
Alaa Elddin Jaber, Department of Medicine, The Specialty Hospital, Amman, Jordan
Lara Abdulhadi, Department of Pharmacy, Al Khalidi Hospital and Medical Center, Amman, Jordan
Omar Dodin, Department of Medicine, Jordan Hospital Medical Center, Amman, Jordan
Amal Matar, Department of Pharmacy, Al Khalidi Hospital and Medical Center, Amman, Jordan
Received: Jul. 5, 2020;       Accepted: Jul. 17, 2020;       Published: Jul. 28, 2020
DOI: 10.11648/j.ijidt.20200503.14      View  19      Downloads  20
Abstract
To measure the rate of unnecessary antimicrobials (UAU), and the effect of the infectious disease consultation. A 17-week multicenter study, patients’ records were reviewed for antimicrobials. A predefined UAU definition was developed. Excluded patients were those on prophylaxis and less than 1-year-old. The outcome is the UAU rate. Confounders were adjusted by Charlson index and APACHE 2 score. The analysis was by Χ2 and Fischer's Exact Tests and multivariate analysis as appropriate. 662 records were reviewed: 169 qualified the necessary antimicrobial use (NAU) and 493 in the UAU categories. The rate of the UAU was 74.5%. The age means differed (53.85 years for the NAU versus 46.48 years for the UAU, P<0.001) without gender difference (P=0.285). The patients in the UAU category were represented more in UTI, SSTI, BSI, and no infection (P<0.05). The commonest UAU subcategory were non-infectious non-febrile conditions 36.71%, influenza-like illnesses, and viral syndromes 20.08%, combination therapy 17.6%. An infectious disease consultation was significantly associated with less UAU (P ≤ 0.004), and less mortality (P<0.05). In conclusion: UAU rate was high, and an infectious disease consultation significantly reduced the UAU rate and mortality.
Keywords
Unnecessary Antimicrobial Use, Stewardship, Infectious Diseases Consult, Mortality
To cite this article
Jamal Wadi Al Ramahi, Oday Abu Ajamieh, Nadine Marrar, Lana Alalamat, Nour Hasan, Alaa Elddin Jaber, Lara Abdulhadi, Omar Dodin, Amal Matar, The Rates of the Unnecessary Antimicrobial Use (UAU) and the Effect of the Infectious Disease Consultations: A Cross-Sectional Study, International Journal of Infectious Diseases and Therapy. Vol. 5, No. 3, 2020, pp. 56-63. doi: 10.11648/j.ijidt.20200503.14
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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