Volume 4, Issue 2, June 2019, Page: 18-22
Effect of Vaccination on Influenza Infection Rate on KSA
Mohammed Ahmed Garout, Community Medicine & Public Health, Faculty of Medicine, Umo Alqurah University, Makkah, KSA
Imad A AlJahdali, Community Medicine & Public Health, Faculty of Medicine, Umo Alqurah University, Makkah, KSA
Magda Rmadan Abdultawab, Microbiology & immunology & Infection Control, Faculty of Medicine, Ainshams University, Cairo, Egypt
Rana Mohammed Garout, Ibn Sina National Collage for Medical Studies, Jeddah, KSA, Saudi Arabia
Raha Mohammed Garout, Ibn Sina National Collage for Medical Studies, Jeddah, KSA, Saudi Arabia
Received: May 16, 2019;       Accepted: Jun. 14, 2019;       Published: Jul. 11, 2019
DOI: 10.11648/j.ijidt.20190402.11      View  128      Downloads  26
Influenza is an acute respiratory disease characterized in its full form by the sudden onset of high fever, coryza, cough, headache, malaise, and inflammation of the upper respiratory tree and trachea. In most cases, pneumonic involvement is not clinically prominent. Aim of study: this Review, we examine the influenza virus infection in cross section study in Riyadh city KSA, This knowledge is used for risk assessments for future, and study effect of influenza vaccine and its implication against influenza virus infection rate STUDY METHODS: A cluster randomized trial involving 1271 children and adolescents and adult, age group between 36 months to 60 years who attend for SMC (Specialized medical center hospital) hospital in ER from January 1 2018, and ended December 31, 2018. History was taken for received vaccine or not, and risk factor diseases (Bronchial Asthma, Diabetics, Heart disease, pneumonia, Immunocompromised). NASOPHARNGEAL swab for: Diagnostic tests: rapid antigen testing, reverse transcription polymerase chain reaction (RT-PCR), and rapid molecular assays, and Follow-up for outcome in infected cases Results: the study revealed that 361of 1271 (28.4%) had influenza, 89 patient had H1N1 (7%), 128 patients had influenza A (10.07%) & 144 patients had influenza B (11.32%), one case had H1N1 and Influnza B Detected, 61% had received vaccination., Among 361 diseased cases 137 receive vaccine (37.9%), outcome of case did not need hospital admission, complete recovery for a protective effectiveness of 61% (95% confidence interval [P =.03). overall protective effectiveness of influenza vaccine was 59.3% in children and 66.5% in adult so over all protection 63%, recommendation Routine annual influenza vaccination is recommended for all persons age 6 months and older.
Influenza, Vaccination, Protective Effectiveness, Virus Infection, Respiratory
To cite this article
Mohammed Ahmed Garout, Imad A AlJahdali, Magda Rmadan Abdultawab, Rana Mohammed Garout, Raha Mohammed Garout, Effect of Vaccination on Influenza Infection Rate on KSA, International Journal of Infectious Diseases and Therapy. Vol. 4, No. 2, 2019, pp. 18-22. doi: 10.11648/j.ijidt.20190402.11
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Hayward AC, Fragaszy EB, Bermingham A, et al.: Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med. 2014; 2 (6): 445-54.
Ducatez MF, Pelletier C, Meyer G.: Influenza D virus in cattle, France, 2011-2014. Emerg Infect Dis. 2015; 21 (2): 368-71.
Cowling B, Chan K-H, Fang VJ, Cheun CYK, Fung ROP, Wai W. et al.: Facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial Annals of Internal medicine 2016; 151: 437-446.
Kilbourne E.: Influenza pandemics of the 20th century. Emerg Infect Dis; 2006.
Thompson WW, Shay DK, Weintraub E, et al.: Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA. 2013; 289 (2): 179-86.
Webster RG, Monto AS, Braciale TJ, Lamb RA (editors). Textbook of Influenza. 2nd ed. Chichester: John Wiley & Sons Ltd; 2013.
Nair H, Abdullah Brooks W, Katz M et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. lancet 2011; 378: 1917–3.
WHO: recommended surveillance standards, 2017.
Center for Disease Control and Prevention (CDC (Influenza (Flu) – Center for Disease Control and Prevention (CDC), USA, March 1, 2018).
www.health.qld.gov.au/clinical-practice/guidelines-procedures/diseases-infection/immunisation/research, 2018.
http://www.nfid.org/influenza, 2019.
Chartrand C, Leeflang MM, Minion J, Brewer T, Pai M.: Accuracy of rapid influenza diagnostic tests: a meta-analysis. Ann Intern Med. 2012 Apr 3; 156 (7): 500-11.
Merckx J, Wali R, Schiller I, Caya C, Gore GC, Chartrand C et al.: Diagnostic Accuracy of Novel and Traditional Rapid Tests for Influenza Infection Compared With Reverse Transcriptase Polymerase Chain Reaction: A Systematic Review and Meta-analysis. Ann Intern Med. 2017 Sep 19; 167 (6): 394.
lancet, http://doii.orgl10.1016/so140-6736, 2018.
Browse journals by subject