Volume 4, Issue 2, June 2019, Page: 18-22
Effect of Vaccination on Influenza Infection Rate on KSA
Mohammed Ahmed Garout, Community Medicine & Public Health, Faculty of Medicine, Umo Alqurah University, Makkah, KSA
Emad Algahdaly, Community Medicine & Public Health, Faculty of Medicine, Umo Alqurah University, Makkah, KSA
Magda Rmadan Abdultawab, Microbiology & immunology & Infection Control, Faculty of Medicine, Ainshams University, Cairo, Egypt
Rana Mohammed Garout, Ibn Sina National Collage for Medical Studies, Jeddah, KSA, Saudi Arabia
Raha Mohammed Garout, Ibn Sina National Collage for Medical Studies, Jeddah, KSA, Saudi Arabia
Received: May 16, 2019;       Accepted: Jun. 14, 2019;       Published: Jul. 11, 2019
DOI: 10.11648/j.ijidt.20190402.11      View  55      Downloads  16
Abstract
Influenza is an acute respiratory disease characterized in its full form by the sudden onset of high fever, coryza, cough, headache, malaise, and inflammation of the upper respiratory tree and trachea. In most cases, pneumonic involvement is not clinically prominent. Aim of study: this Review, we examine the influenza virus infection in cross section study in Riyadh city KSA, This knowledge is used for risk assessments for future, and study effect of influenza vaccine and its implication against influenza virus infection rate STUDY METHODS: A cluster randomized trial involving 1271 children and adolescents and adult, age group between 36 months to 60 years who attend for SMC (Specialized medical center hospital) hospital in ER from January 1 2018, and ended December 31, 2018. History was taken for received vaccine or not, and risk factor diseases (Bronchial Asthma, Diabetics, Heart disease, pneumonia, Immunocompromised). NASOPHARNGEAL swab for: Diagnostic tests: rapid antigen testing, reverse transcription polymerase chain reaction (RT-PCR), and rapid molecular assays, and Follow-up for outcome in infected cases Results: the study revealed that 361of 1271 (28.4%) had influenza, 89 patient had H1N1 (7%), 128 patients had influenza A (10.07%) & 144 patients had influenza B (11.32%), one case had H1N1 and Influnza B Detected, 61% had received vaccination., Among 361 diseased cases 137 receive vaccine (37.9%), outcome of case did not need hospital admission, complete recovery for a protective effectiveness of 61% (95% confidence interval [P =.03). overall protective effectiveness of influenza vaccine was 59.3% in children and 66.5% in adult so over all protection 63%, recommendation Routine annual influenza vaccination is recommended for all persons age 6 months and older.
Keywords
Influenza, Vaccination, Protective Effectiveness, Virus Infection, Respiratory
To cite this article
Mohammed Ahmed Garout, Emad Algahdaly, Magda Rmadan Abdultawab, Rana Mohammed Garout, Raha Mohammed Garout, Effect of Vaccination on Influenza Infection Rate on KSA, International Journal of Infectious Diseases and Therapy. Vol. 4, No. 2, 2019, pp. 18-22. doi: 10.11648/j.ijidt.20190402.11
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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