Volume 3, Issue 2, June 2018, Page: 40-44
Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria
Sheyin Zakka, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria; School of Medicine and Allied Health Sciences, University of the Gambia, Banjul, Gambia
Frama Ishaku, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Essien Unyime Cosmas, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Shindang John, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Bigwan Emmanuel Isa, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Received: Aug. 8, 2018;       Accepted: Aug. 24, 2018;       Published: Sep. 17, 2018
DOI: 10.11648/j.ijidt.20180302.14      View  328      Downloads  29
Abstract
Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.
Keywords
Hepatitis, HBV, Hepatocytes, Hepatocellular Carcinoma, HBsAg, OnSite HBV 5-Parameter Rapid Test
To cite this article
Sheyin Zakka, Frama Ishaku, Essien Unyime Cosmas, Shindang John, Bigwan Emmanuel Isa, Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria, International Journal of Infectious Diseases and Therapy. Vol. 3, No. 2, 2018, pp. 40-44. doi: 10.11648/j.ijidt.20180302.14
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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